Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | NCI_CANONICAL NF-KAPPAB PATHWAY |
| Enrichment Score (ES) | -0.729408 |
| Normalized Enrichment Score (NES) | -1.6010991 |
| Nominal p-value | 0.004032258 |
| FDR q-value | 0.14327426 |
| FWER p-Value | 0.788 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CYLD | 6590079 | 2137 | 1.107 | -0.0853 | No | ||
| 2 | NFKB1 | 5420358 | 2462 | 0.934 | -0.0777 | No | ||
| 3 | UBE2D3 | 3190452 | 3104 | 0.570 | -0.0969 | No | ||
| 4 | ARRB2 | 2060441 | 3420 | 0.442 | -0.1020 | No | ||
| 5 | CHUK | 7050736 | 3694 | 0.353 | -0.1072 | No | ||
| 6 | TNF | 6650603 | 4857 | 0.148 | -0.1658 | No | ||
| 7 | BCL3 | 3990440 | 5360 | 0.110 | -0.1898 | No | ||
| 8 | PIK3R1 | 4730671 | 7432 | 0.039 | -0.3002 | No | ||
| 9 | XPO1 | 540707 | 7976 | 0.029 | -0.3287 | No | ||
| 10 | RAN | 2260446 4590647 | 9782 | 0.000 | -0.4258 | No | ||
| 11 | MALT1 | 4670292 | 11838 | -0.034 | -0.5355 | No | ||
| 12 | ATM | 3610110 4050524 | 11988 | -0.038 | -0.5425 | No | ||
| 13 | SRC | 580132 | 12487 | -0.050 | -0.5680 | No | ||
| 14 | PIK3CA | 6220129 | 12692 | -0.056 | -0.5774 | No | ||
| 15 | FBXW11 | 6450632 | 12804 | -0.059 | -0.5818 | No | ||
| 16 | SYK | 6940133 | 12894 | -0.062 | -0.5849 | No | ||
| 17 | REL | 360707 | 13327 | -0.079 | -0.6061 | No | ||
| 18 | BIRC2 | 2940435 4730020 | 13602 | -0.093 | -0.6183 | No | ||
| 19 | PRKCA | 6400551 | 13968 | -0.118 | -0.6348 | No | ||
| 20 | ERC1 | 1580170 2630717 6110762 6840280 | 14430 | -0.159 | -0.6553 | No | ||
| 21 | NOD2 | 2510050 | 14972 | -0.257 | -0.6776 | No | ||
| 22 | RIPK2 | 5050072 6290632 | 15296 | -0.354 | -0.6855 | No | ||
| 23 | IKBKG | 3450092 3840377 6590592 | 15750 | -0.544 | -0.6952 | No | ||
| 24 | TRAF6 | 4810292 6200132 | 16386 | -0.933 | -0.7044 | Yes | ||
| 25 | IKBKB | 6840072 | 16418 | -0.950 | -0.6806 | Yes | ||
| 26 | MAPK14 | 5290731 | 16662 | -1.120 | -0.6636 | Yes | ||
| 27 | NFKBIA | 1570152 | 17332 | -1.860 | -0.6497 | Yes | ||
| 28 | MAP3K14 | 5890435 | 17399 | -1.981 | -0.6002 | Yes | ||
| 29 | RELB | 1400048 | 17503 | -2.129 | -0.5486 | Yes | ||
| 30 | NFKB2 | 2320670 | 17622 | -2.349 | -0.4919 | Yes | ||
| 31 | RELA | 3830075 | 17641 | -2.379 | -0.4291 | Yes | ||
| 32 | LCK | 3360142 | 17786 | -2.667 | -0.3653 | Yes | ||
| 33 | BCL10 | 2360397 | 18080 | -3.458 | -0.2883 | Yes | ||
| 34 | TNFRSF1A | 1090390 6520735 | 18474 | -5.755 | -0.1551 | Yes | ||
| 35 | TNFAIP3 | 2900142 | 18498 | -6.065 | 0.0064 | Yes |
